Fig. 2
From: Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity
Induction of megakaryocytic or erythroid differentiation in erythroleukemia cell line HEL by A1541 and A1543. a-c Treatment of the erythroleukemic cell lines HEL with A1542–43 increases the percentage of CD71/CD235 positive erythroid cells (a), as well as CD41+ (b) and CD61+ (c) megakaryocytic cells after 24 h. Cedrelone had no effect on either erythroid or megakaryocytic differentiation (a-c)