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Table 4 Crude and adjusted analysis of the association between age and preoperative radiotherapy in stage II and III rectal cancer patients

From: Impact of age on the use of adjuvant treatments in patients undergoing surgery for colorectal cancer: patients with stage III colon or stage II/III rectal cancer

 

Preoperative radiotherapy in stage II and III rectal cancer

4A. Univariate analysis

4B. Multivariate analysis

n (%)

P value

Odds Ratio (95% CI)

P value

Age, years

  < 65

138 (68.0)

< 0.0005b

1

 

 65–80

142 (60.4)

 

0.9 (0.6–1.4)

0.74

  > 80

27 (42.2)

 

0.5 (0.3–0.8)

0.004

Sex

 Male

205 (60.7)

0.85a

  

 Female

102 (61.8)

   

Deprivation index

 Quartile 1

50 (61.7)

0.31b

  

 Quartile 2

86 (54.8)

   

 Quartile 3

94 (61.8)

   

 Quartile 4

57 (65.5)

   

Level of education

 No formal

31 (62.0)

0.78b

  

 Primary

164 (60.5)

   

 Secondary

28 (65.1)

   

 University

25 (55.6)

   

Living arrangements

 Living alone

30 (60.0)

0.88a

  

 Living with others

217 (61.3)

   

Family history of cancer

 No

147 (55.3)

0.005a

1

 

 Yes

136 (68.3)

 

1.5 (1.0–2.1)

0.05

Screening

 No

262 (61.6)

0.30a

  

 Yes

29 (53.7)

   

Smoking habits

 Never smoker

136 (60.7)

0.31a

  

 Current smoker

56 (68.3)

   

 Ex-smoker

113 (58.5)

   

Alcohol

 No

264 (61.4)

0.77a

  

 Yes

32 (59.3)

   

Charlson index

 0

179 (64.6)

0.03b

1

 

 1

74 (60.7)

 

0.9 (0.6–1.4)

0.77

  ≥ 2

54 (51.9)

 

0.9 (0.5–1.7)

0.88

ASA class

 I-II

187 (63.8)

0.12b

1

 

 III

106 (57.6)

 

0.9 (0.6–1.2)

0.39

 IV

7 (50.0)

 

0.8 (0.3–2.4)

0.68

Degree of differentiation

 Low grade

201 (59.5)

0.76a

  

 High grade

29 (56.9)

   

Histological classification

 Adenocarcinoma

268 (60.8)

0.29a

  

 Mucinous adenocarcinoma

13 (52.0)

   

Stage

 II

75 (45.7)

< 0.0005a

1

 

 III

232 (68.4)

 

2.8 (1.5–4.9)

0.001

Cancer committee

 No

84 (57.9)

0.48a

  

 Yes

205 (61.6)

   

Surgeon’s profile

 General

91 (61.1)

1.0a

  

 Coloproctologist

201 (61.3)

   
  1. aPearson Chi-square test
  2. bChi-square test for trends