| Preoperative radiotherapy in stage II and III rectal cancer | |||
---|---|---|---|---|
4A. Univariate analysis | 4B. Multivariate analysis | |||
n (%) | P value | Odds Ratio (95% CI) | P value | |
Age, years | ||||
  < 65 | 138 (68.0) | < 0.0005b | 1 |  |
 65–80 | 142 (60.4) |  | 0.9 (0.6–1.4) | 0.74 |
  > 80 | 27 (42.2) |  | 0.5 (0.3–0.8) | 0.004 |
Sex | ||||
 Male | 205 (60.7) | 0.85a |  |  |
 Female | 102 (61.8) |  |  |  |
Deprivation index | ||||
 Quartile 1 | 50 (61.7) | 0.31b |  |  |
 Quartile 2 | 86 (54.8) |  |  |  |
 Quartile 3 | 94 (61.8) |  |  |  |
 Quartile 4 | 57 (65.5) |  |  |  |
Level of education | ||||
 No formal | 31 (62.0) | 0.78b |  |  |
 Primary | 164 (60.5) |  |  |  |
 Secondary | 28 (65.1) |  |  |  |
 University | 25 (55.6) |  |  |  |
Living arrangements | ||||
 Living alone | 30 (60.0) | 0.88a |  |  |
 Living with others | 217 (61.3) |  |  |  |
Family history of cancer | ||||
 No | 147 (55.3) | 0.005a | 1 |  |
 Yes | 136 (68.3) |  | 1.5 (1.0–2.1) | 0.05 |
Screening | ||||
 No | 262 (61.6) | 0.30a |  |  |
 Yes | 29 (53.7) |  |  |  |
Smoking habits | ||||
 Never smoker | 136 (60.7) | 0.31a |  |  |
 Current smoker | 56 (68.3) |  |  |  |
 Ex-smoker | 113 (58.5) |  |  |  |
Alcohol | ||||
 No | 264 (61.4) | 0.77a |  |  |
 Yes | 32 (59.3) |  |  |  |
Charlson index | ||||
 0 | 179 (64.6) | 0.03b | 1 |  |
 1 | 74 (60.7) |  | 0.9 (0.6–1.4) | 0.77 |
  ≥ 2 | 54 (51.9) |  | 0.9 (0.5–1.7) | 0.88 |
ASA class | ||||
 I-II | 187 (63.8) | 0.12b | 1 |  |
 III | 106 (57.6) |  | 0.9 (0.6–1.2) | 0.39 |
 IV | 7 (50.0) |  | 0.8 (0.3–2.4) | 0.68 |
Degree of differentiation | ||||
 Low grade | 201 (59.5) | 0.76a |  |  |
 High grade | 29 (56.9) |  |  |  |
Histological classification | ||||
 Adenocarcinoma | 268 (60.8) | 0.29a |  |  |
 Mucinous adenocarcinoma | 13 (52.0) |  |  |  |
Stage | ||||
 II | 75 (45.7) | < 0.0005a | 1 |  |
 III | 232 (68.4) |  | 2.8 (1.5–4.9) | 0.001 |
Cancer committee | ||||
 No | 84 (57.9) | 0.48a |  |  |
 Yes | 205 (61.6) |  |  |  |
Surgeon’s profile | ||||
 General | 91 (61.1) | 1.0a |  |  |
 Coloproctologist | 201 (61.3) |  |  |  |