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Table 2 Summary of univariate and multivariate Cox regression analysis of OS duration in all ccRCCs

From: Cyclin-dependent kinase 5 acts as a promising biomarker in clear cell Renal Cell Carcinoma

Variables

Univariate analysis

Multivariate analysis

HR

(95% CI)

p*

HR

(95% CI)

p*

CDK5 expression (low vs high)

0.486

0.214–1.104

0.085

 

p21 expression (Low vs High)

0.375

0.142–0.985

0.047

0.369

0.162–0.839

0.078

CDK5/p21expression (CLPL vs Other)

0.310

0.143–0.672

0.003

0.229

0.102–0.515

< 0.001

Age (< 55 vs > 55)

1.047

1.011–1.084

0.010

1.022

0.986–1.060

0.237

TNM stage (I + II vs III + IV)

6.972

2.935–16.563

< 0.001

2.920

1.129–7.556

0.027

Fuhrman grade (I + II vs III + IV)

5.043

2.359–10.781

0.001

3.299

0.776–6.254

0.138

Tumor size (< 4 vs > 4)

4.247

1.721–10.479

0.002

3.490

1.329–9.164

0.011

  1. CLPL CDK5 low/p21 low, HR hazard ratio, 95% CI 95% confidence interval