From: Cyclin-dependent kinase 5 acts as a promising biomarker in clear cell Renal Cell Carcinoma
Characteristic | Patients | Tumoral CDK5 expression | Tumoral p21 expression | ||||||
---|---|---|---|---|---|---|---|---|---|
n | % | Low | High | P-value | Low | High | P-value | ||
All patients | 150 | 100 | 83 | 67 | 97 | 53 | |||
Gender | 0.661 | 0.289 | |||||||
Male | 107 | 71.3 | 58 | 49 | 72 | 35 | |||
Female | 43 | 28.7 | 25 | 18 | 25 | 18 | |||
Age (years) | 0.624 | 0.356 | |||||||
≤55 | 66 | 44 | 38 | 28 | 40 | 26 | |||
> 55 | 84 | 56 | 45 | 39 | 57 | 27 | |||
TNM stage | 0.042 | 0.172 | |||||||
I + II | 138 | 92 | 73 | 65 | 88 | 50 | |||
III + IV | 12 | 8 | 10 | 2 | 10 | 2 | |||
pT stage | 0.066 | 0.435 | |||||||
T1 + T2 | 139 | 92.7 | 74 | 65 | 89 | 50 | |||
T3 + T4 | 11 | 7.3 | 9 | 2 | 8 | 3 | |||
pN stage | 0.439 | 0.279 | |||||||
N0 | 147 | 98 | 82 | 65 | 96 | 50 | |||
N1 | 3 | 2 | 1 | 2 | 1 | 2 | |||
pM stage | ___ | ___ | |||||||
M0 | 150 | 100 | 84 | 66 | 97 | 53 | |||
M1 | 0 | 0 | 0 | 0 | 0 | 0 | |||
Fuhrman grade | 0.035 | 0.026 | |||||||
I + II | 108 | 72 | 54 | 54 | 64 | 44 | |||
III + IV | 42 | 28 | 29 | 13 | 33 | 9 | |||
Tumor size (cm) | 0.250 | 0.393 | |||||||
≤4 | 75 | 50 | 45 | 30 | 51 | 24 | |||
> 4 | 75 | 50 | 38 | 37 | 46 | 29 |