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Table 1 Association between KLK5 mRNA expression levels and clinical characteristics in patients with advanced HGSOC stage FIGO III/IV

From: Quantitative assessment and clinical relevance of kallikrein-related peptidase 5 mRNA expression in advanced high-grade serous ovarian cancer

Clinical parameters

No. of patients

KLK5

Low/high a

Age

 

p = 0.476

 ≤ 60 years

58

35 (60%)/23 (40%)

 > 60 years

80

53 (66%)/27 (34%)

Residual tumor mass

 

p = 0.041

 0 mm

70

51 (73%)/19 (27%)

 > 0 mm

66

37 (56%)/29 (44%)

Ascites fluid volume

 

p = 0.087

 ≤ 500 ml

77

54 (70%)/23 (30%)

 > 500 ml

54

30 (56%)/24 (44%)

FIGO stage

 

p = 0.051

 IIIA + IIIB

15

13 (87%)/2 (13%)

 IIIC + IV

123

75 (61%)/48 (39%)

  1. Due to missing values, numbers do not always add up to n = 138
  2. a Categorized into low- and high-expressing groups by tertiles 1 + 2 versus tertile 3
  3. Significant p-value is indicated in bold