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Table 1 Association between KLK5 mRNA expression levels and clinical characteristics in patients with advanced HGSOC stage FIGO III/IV

From: Quantitative assessment and clinical relevance of kallikrein-related peptidase 5 mRNA expression in advanced high-grade serous ovarian cancer

Clinical parameters No. of patients KLK5
Low/high a
Age   p = 0.476
 ≤ 60 years 58 35 (60%)/23 (40%)
 > 60 years 80 53 (66%)/27 (34%)
Residual tumor mass   p = 0.041
 0 mm 70 51 (73%)/19 (27%)
 > 0 mm 66 37 (56%)/29 (44%)
Ascites fluid volume   p = 0.087
 ≤ 500 ml 77 54 (70%)/23 (30%)
 > 500 ml 54 30 (56%)/24 (44%)
FIGO stage   p = 0.051
 IIIA + IIIB 15 13 (87%)/2 (13%)
 IIIC + IV 123 75 (61%)/48 (39%)
  1. Due to missing values, numbers do not always add up to n = 138
  2. a Categorized into low- and high-expressing groups by tertiles 1 + 2 versus tertile 3
  3. Significant p-value is indicated in bold