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Table 4 Mean values at baseline, and between-group differences and at the end of chemotherapy, the end of radiotherapy and at 6- and 12-month follow-up for behavioral outcomes

From: Short- and long-term impact of adapted physical activity and diet counseling during adjuvant breast cancer therapy: the “APAD1” randomized controlled trial

 T0
Baseline
T1–18 weeks
Mid-intervention
T2–26 weeks
End of intervention
T3–52 weeks
6-month follow-up
T4–78 weeks
1-year follow-up
Mean (SD)AMD (95% CI)*EFPAMD (95% CI)*EFPAMD (95% CI)*EFPAMD (95% CI)*EFP
Declared physical activity in MET.min/semaine (GPAQ)
Total (MET.min/wk) UC1671 (1788)5.82 (−0.04; 11.67)0.160.1084.31 (−1.62; 10.23)0.120.2193.92 (−2.7; 10.55)0.100.283−1.05 (−8.51; 6.41)−0.020.936
APAD1506 (1617)            
Moderate intensity (MET.min/wk)UC1659 (1791)293.7 (−140.2; 727.6)0.110.179220.8 (−219.5; 661)0.080.273418.1 (−87.9; 924.2)0.140.110105.4 (− 489.2; 700)0.030.550
APAD1428 (1427)            
Leisure (MET.min/wk)UC663 (1214)8.77 (3.87; 13.66)0.290.0019.61 (4.66; 14.56)0.320.0003.89 (−1.62; 9.39)0.120.0712.29 (−3.88; 8.46)0.060.203
APAD343 (559)            
Sedentary time (min/day)UC431 (178)28.8 (−18.9; 76.6)0.100.311−28.1 (−78.0; 21.4)−0.090.450−31.4 (−91.2; 28.3)−0.090.440−55.0 (− 126.2; 16.3)−0.130.205
APAD415 (143)            
Achieved physical activity for an average day (ArmBand)
Total (min) UC88 (79)   0.24 (−0.11; 0.59)0.110.166      
APAD84 (62)            
Moderate intensity (min)UC86 (76)   14.6 (−11.6; 40.9)0.090.094      
APAD83 (61)            
Average intensity (MET.h)UC2 (0)   0.05 (−0.08; 0.18)0.060.279      
APAD2 (0)            
Sedentary time (min)UC776 (211)   13.3 (−50.9; 77.5)0.030.432      
APAD755 (162)            
Nutrient intake per day (3-day record)
Total energy (kcal) UC1418.2 (414.1)   −0.03 (−0.11; 0.05)−0.070.248   −0.03 (− 0.23; 0.16)−0.030.600
APAD1538.6 (427.4)            
Proteins (g)UC64.1 (20.2)   3.89 (−0.85; 8.63)0.130.367   2.2 (−7.09; 11.5)0.040.830
APAD66.7 (17.4)            
Animal proteins (g)UC35.4 (19.6)   3.35 (−1.69; 8.39)0.110.366   8.92 (−5.49; 23.33)0.100.274
APAD36.9 (17.4)            
Vegetal proteins (g)UC12.8 (7.7)   −0.03 (−1.92; 1.85)0.000.885   −1.45 (−6.28; 3.39)−0.050.539
APAD13.3 (6.9)            
Lipids (g)UC60 (20.6)   −4.9 (−10.3; 0.54)−0.150.091   −11.2 (−23.6; 1.1)− 0.150.066
APAD64.2 (22.5)            
Saturated fat (g) UC21.9 (7.8)   −0.02 (−0.13; 0.09)−0.030.517   −0.05 (− 0.34; 0.24)−0.030.648
APAD24.8 (9.8)            
Monounsaturated fat (g)UC22.7 (8.3)   −2.27 (−4.61; 0.07)−0.160.081   −4.28 (−9.32; 0.75)− 0.140.089
APAD24.1 (9.6)            
Polyunsaturated fat (g) UC7.8 (7.2)   −0.07 (−0.21; 0.07)−0.080.408   −0.05 (− 0.35; 0.25)−0.030.748
APAD7 (3.2)            
Total carbohydrates (g)UC145.4 (51.6)   −4.17 (−17.09; 8.76)−0.050.365   9.01 (−23.57; 41.59)0.050.692
APAD160.6 (52.6)            
Fibres (g)UC15.2 (5.8)   −0.43 (−2.07; 1.2)−0.040.708   0.35 (−3.58; 4.28)0.010.834
APAD14.7 (5.7)            
  1. Abbreviations: AMD Adjusted Mean Differences, CI Confidence Interval, EF Effect Size, GPAQ Global Physical Activity Questionnaire, APAD Adapted Physical Activity and Diet counseling intervention, UC Usual Care
  2. NOTE: Bold font indicates significant difference
  3. *Baseline value, surgery type and age-adjusted mean differences and their associated 95% confidence interval estimated with linear mixed model
  4. P-value for time*arm interaction estimated with linear mixed model
  5. Log transformed variables: Total physical activity – ArmBand, Total energy – 3-day record, Saturated fat – 3-day record, Polyunsaturated fat – 3-day record, Linoleic acid – 3-day record, Linolenic acid – 3-day record
  6. Square root transformed variables: Total physical activity – GPAQ, Leisure physical activity – GPAQ