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Table 6 pCR Multivariate Analysis

From: Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as predictive and prognostic markers in patients with locally advanced rectal cancer treated with neoadjuvant chemoradiation

Outcome Odds Ratio (95% CI) P-value
NLR
 < 4 ref 0.16
 ≥ 4 0.76 (0.52–1.11)  
PLR
 < 150 ref 0.90
 ≥ 150 1.02 (0.73–1.42)  
Pre-treatment CEA
 < 5 ng/ml ref < 0.01
 ≥ 5 ng/ml 0.38 (0.26–0.55)  
 Unknown 0.71 (0.44–1.14)
Clinical stage
 II ref 0.03
 III 0.67 (0.49–0.92)  
 Unknown 0.29 (0.04–2.29)
  1. CEA Carcinoembryonic antigen, ECOG Eastern Cooperative Oncology Group, NLR Neutrophil-to-lymphocyte ratio, pCR Pathologic complete response, PLR Platelet-to-lymphocyte ratio