Variable |  | Total (n = 1237) | NLR | p-val | PLR | p-val | ||
---|---|---|---|---|---|---|---|---|
<  4 (n = 912, 74%) | ≥ 4 (n = 325, 26%) | <  150 (n = 418, 34%) | ≥ 150 (n = 819, 66%) | |||||
Province, n (%) | Alberta | 595 (48) | 435 (48) | 160 (49) | NS | 226 (54) | 369 (45) | < 0.01 |
British Columbia | 255 (21) | 186 (20) | 69 (21) | Â | 69 (17) | 186 (23) | Â | |
Ontario | 387 (31) | 291 (32) | 96 (30) | Â | 123 (29) | 264 (32) | Â | |
Age, years | Median (range) | 62 (23–88) | 61 (23–88) | 64 (24–87) | < 0.01 | 62 (23–85) | 62 (23–88) | NS |
≥65, n (%) | 482 (39) | 334 (37) | 148 (46) | < 0.01 | 154 (37) | 328 (40) | NS | |
Male, n (%) | Â | 858 (69) | 632 (69) | 226 (70) | NS | 302 (72) | 556 (68) | NS |
BMI, kg/m2 | n = 1130 | ≥ 25, n (%) | 729 (59) | 553 (61) | 176 (54) | NS | 272 (65) | 457 (56) | < 0.01 |
ECOG PS, n (%) | 0 | 524 (42) | 398 (44) | 126 (39) | < 0.01 | 188 (45) | 336 (41) | NS |
1 | 466 (38) | 344 (38) | 122 (38) | Â | 160 (38) | 306 (37) | Â | |
2+ | 62 (5) | 32 (4) | 30 (9) | Â | 13 (3) | 49 (6) | Â | |
Unknown | 185 (15) | 138 (15) | 47 (14) | Â | 57 (14) | 128 (16) | Â | |
Distance from anal verge, n (%) | n = 1166 | Median (range) | 6 (0–30) | 6 (0–30) | 6 (0–25) | NS | 6 (0–20) | 6 (0–30) | NS |
<  5 cm | 415 (34) | 306 (33) | 109 (34) | NS | 137 (33) | 278 (34) | NS | |
5–10 cm | 507 (41) | 381 (42) | 126 (39) |  | 178 (43) | 329 (40) |  | |
>  10 cm | 244 (20) | 181 (20) | 63 (19) |  | 84 (20) | 160 (20) |  | |
Unknown | 71 (6) | 44 (5) | 27 (8) | Â | 19 (4) | 52 (6) | Â | |
Pre-treatment CEA, n (%) | n = 1093 | Median (range) | 4 (0–1133) | 3 (0–857) | 4 (0–1133) | NS | 3 (0–468) | 4 (0–1133) | NS |
<  5 ng/mL | 667 (54) | 510 (56) | 157 (48) | NS | 230 (55) | 437 (53) | NS | |
≥ 5 ng/mL | 426 (34) | 301 (33) | 125 (39) |  | 142 (34) | 284 (35) |  | |
Unknown | 144 (12) | 101 (11) | 43 (13) | Â | 46 (11) | 98 (12) | Â | |
Clinical stage, n (%) | II | 341 (28) | 253 (28) | 88 (27) | NS | 119 (28) | 222 (27) | NS |
III | 880 (71) | 644 (71) | 236 (73) | Â | 291 (70) | 589 (72) | Â | |
Unknown | 16 (1) | 15 (2) | 1 (0) | Â | 8 (2) | 8 (1) | Â | |
Hemoglobin (g/dl) | Median (range) | 136 (68–183) | 137 (68–183) | 131 (68–178) | < 0.01 | 140 (93–183) | 133 (68–178) | < 0.01 |