Table 1 Authentication profile for the selected clones vs. MDA-MB-231 parental cell line. Characterization of the clonal cell lines (GFP C3, mKO E10 and Sapphire D7) versus parental cell line (MDA-MB-231, also named ATCC® HTB-26) by STR profile evaluation (first column): number of shared alleles and percent match
From: The role of clonal communication and heterogeneity in breast cancer
STR profile | Expected: ATCC® HTB-26 | MDA-MB-231 | GFP C3 | mKO E10 | Sapphire D7 |
|---|---|---|---|---|---|
D5S818 | 12 | 12 | 12 | 12 | 12 |
D13S317 | 13 | 13 | 13 | 13 | 13 |
D7S820 | 8,9 | 8 | 8 | 8 | 8 |
D16S539 | 12 | 12 | 12 | 12 | 12 |
vWA | 15,18 | 15 | 15 | 15,16 | 15 |
TH01 | 7,9.3 | 7,9.3 | 7,9.3 | 7,9.3 | 7,9.3 |
TPOX | 8,9 | 8,9 | 8,9 | 8,9 | 8,9 |
CSF1PO | 12,13 | 12,13 | 12,13 | 12,13 | 12,13 |
D21S11 | 30,33.2 | 30,33.2 | 30,33.2 | 30,33.2 | 30,33.2 |
Amelogenin | x | x | x | x | x |
Number of shared alleles | 14 | 14 | 14 | 14 | |
Number of alleles in database | 16 | 16 | 16 | 16 | |
Percent match | 87% | 87% | 87% | 87% | |