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Table 5 Univariate and multivariate analysis of predictors of overall survival outcome after caudate lobe ablation in patients with HCC

From: Predictive factors of treatment outcomes after percutaneous ablation of hepatocellular carcinoma in the caudate lobe: a retrospective study

Factors

Univariate

Multivariate

P value

HR

95%CI

P value

Gender(M/F)

0.880

   

Age(≤60/>60y)

0.917

   

Tumor type (naïve/recurrent)

0.137

   

Surgery history of liver (Y/N)

0.564

   

Etiology (Hepatitis/others)

0.315

   

Liver cirrhosis (Y/N)

0.229

   

Antiviral treatment (Y/N)

0.122

   

ECOG performance status (0/1)

0.877

   

Child-Pugh (A/B)

0.292

   

BCLC stage of primary HCC (A/B)

0.873

   

AFP (≥400/< 400 μg/L)

0.283

   

PLT (≥100/< 100 × 109/L)

0.529

   

PT (≤14/> 14 s)

0.901

   

ALB (≤35/> 35 g/L)

0.254

   

ALT (≤40/> 40 IU/L)

0.518

   

TB (≤17.1/> 17.1 mol/L)

0.886

   

Tumor number (single /multiple)

0.101

   

Location (Paracaval portion/ Caudate process/ Spiegel’s lobe)

0.069

   

Tumor size (≤2 cm /> 2 cm)

0.720

   

Puncture approach (LA/ RA/ combination approach)

0.809

   

Treatment strategy

RFA/ EA/ RFA-EA

0.960

   

EA/RFA or RFA-EA

0.807

   

RFA or EA/RFA-EA

0.529

   

AM (≥ 5 mm / < 5 mm)

0.189

   

LTP (Y/N)

0.890

   

Major complication (Y/N)

0.172

   
  1. HBV hepatitis B virus, HCV hepatitis C virus, ECOG East Coast Oncology Group, BCLC Barcelona Clinic Liver Cancer, AFP alpha-fetoprotein, PLT platelets, PT prothrombin time, ALB albumin, ALT alanine aminotransferase, TB total bilirubin, LA left lobe approach, RA right intercostal approach, EA ethanol ablation, RFA radiofrequency ablation, RFA-EA combination of RFA and EA, AM ablative margin, LTP local tumor progression