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Table 3 Univariate and multivariate analysis of predictors of LTP after caudate lobe ablation

From: Predictive factors of treatment outcomes after percutaneous ablation of hepatocellular carcinoma in the caudate lobe: a retrospective study

Factors

Univariate

Multivariate

P value

HR

95%CI

P value

Gender(M/F)

0.401

   

Age(≤60/>60y)

0.811

   

Tumor type (naive/recurrent)

0.846

   

Surgery history of liver (Y/N)

0.655

   

Etiology (Hepatitis/others)

0.821

   

Liver cirrhosis (Y/N)

0.499

   

Antiviral treatment (Y/N)

0.539

   

ECOG performance status (0/1)

0.768

   

Child-Pugh (A/B)

0.998

   

BCLC stage of primary HCC (A/B)

0.661

   

AFP (≥400/< 400 μg/L)

0.432

   

PLT (≥100/< 100 × 109/L)

0.530

   

PT (≤14/> 14 s)

0.877

   

ALB (≤35/> 35 g/L)

0.280

   

ALT (≤40/> 40 IU/L)

0.162

   

TB (≤17.1/> 17.1 mol/L)

0.616

   

Tumor number (single /multiple)

0.336

   

Location (Paracaval portion/ Caudate process/ Spiegel’s lobe)

0.466

   

Tumor size (≤2 cm /> 2 cm)

0.029

3.667

1.043–12.889

0.043

Puncture approach (LA/ RA/ combination approach)

0.921

   

Treatment strategy

RFA/ EA/ RFA-EA

0.099

–

–

–

EA/RFA or RFA-EA

0.223

   

RFA or EA/RFA-EA

0.054

–

–

–

AM (≥ 5 mm / < 5 mm)

0.336

   
  1. HBV hepatitis B virus, HCV hepatitis C virus, ECOG East Coast Oncology Group, BCLC Barcelona Clinic Liver Cancer, AFP alpha-fetoprotein, PLT platelets, PT prothrombin time, ALB albumin, ALT alanine aminotransferase, TB total bilirubin, LA left lobe approach, RA right intercostal approach, EA ethanol ablation, RFA radiofrequency ablation, RFA-EA combination of RFA and EA, AM ablative margin