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Table 3 Cox proportional hazards regression for overall and cancer-specific mortality of leiomyosarcoma and carcinosarcoma in the 1:1 propensity score matching sample

From: Outcome of adjuvant radiotherapy after total hysterectomy in patients with uterine leiomyosarcoma or carcinosarcoma: a SEER-based study

 

Leiomyosarcoma (n = 180)

Carcinosarcoma (n = 856)

Overall b

Cancer-specific c

Overall b

Cancer-specific c

Variables

HR (95% CI)

P-value

aHR (95% CI)

P-value

HR (95% CI)

P-value

aHR (95% CI)

P-value

Adjuvant radiotherapy

 No treatment

reference

 

reference

 

reference

 

reference

 

 EBRT alone

0.71 (0.33, 1.54)

0.386

0.69 (0.27, 1.79)

0.447

0.65 (0.45, 0.93)

0.020

0.78 (0.50, 1.22)

0.274

 Brachytherapy alone

0.68 (0.14, 3.30)

0.633

0.45 (0.05, 3.93)

0.469

0.62 (0.40, 0.95)

0.029

0.60 (0.34, 1.05)

0.074

 Combination radiotherapy a

NA

NA

NA

NA

0.47 (0.26, 0.85)

0.013

0.67 (0.33, 1.33)

0.250

  1. aHR adjusted hazard ratio, CI confidence interval, EBRT external beam radiation therapy
  2. aCombination radiotherapy: combination of EBRT and either radioactive implants or radioisotopes
  3. bUnivariate regression model
  4. cRace was adjusted for in multivariate regression model
  5. NA: not available because no patient died during the study period
  6. Unknown data for adjuvant radiotherapy were not shown in the table
  7. Bold text indicates a significant difference with a p-value less than 0.05 compared to the reference group