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Table 1 The relationship between the pathological parameters and higher tumor grading

From: Clinical significance of the histological and molecular characteristics of ependymal tumors: a single institution case series from China

  Grade III casesa P value
Cellularity low 6/15 0.037
moderate 10/16
high 19/22
Atypia mild 8/18 0.049
moderate 13/20
severe 13/15
Necrosis present 22/24 <0.001
absent 12/29
Mitosis ≥5/2mm2 18/21 0.016
<5/2mm2 16/32
Vascular proliferation Present 19/21 0.002
Absent 15/32
Ki67 index ≥6% 19/20 <0.001
< 6% 14/38
RELA fusions Positive 17/19 0.001
Negative 20/48
  1. a: Some cases were lost due to inadequate tissue for testing or other reasons