BMC Cancer

Table 1 The relationship between the pathological parameters and higher tumor grading

From: Clinical significance of the histological and molecular characteristics of ependymal tumors: a single institution case series from China

		Grade III cases^a	P value
Cellularity	low	6/15	0.037
	moderate	10/16
	high	19/22
Atypia	mild	8/18	0.049
	moderate	13/20
	severe	13/15
Necrosis	present	22/24	<0.001
Necrosis	absent	12/29	<0.001
Mitosis	≥5/2mm²	18/21	0.016
Mitosis	<5/2mm²	16/32	0.016
Vascular proliferation	Present	19/21	0.002
Vascular proliferation	Absent	15/32	0.002
Ki67 index	≥6%	19/20	<0.001
Ki67 index	< 6%	14/38	<0.001
RELA fusions	Positive	17/19	0.001
RELA fusions	Negative	20/48	0.001

^a: Some cases were lost due to inadequate tissue for testing or other reasons

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ISSN: 1471-2407

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