Variable | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | p value | |
Gender (Female vs Male) | 1.11 | 0.69–1.82 | 0.673 | 0.87 | 0.67–1.13 | 0.289 |
Age (≥65 vs < 65) | 1.01 | 0.61–1.67 | 0.963 | 1.16 | 0.67–2.00 | 0.606 |
Tumor location (colon vs rectum) | 1.09 | 0.64–1.84 | 0.751 | |||
Tumor grade (poor vs moderate to well) | 18.8 | 6.99–50.7 | < 0.001* | 3.27 | 0.98–10.9 | 0.053 |
Tumor stage (T4 vs T1 to T3) | 4.78 | 2.77–8.27 | < 0.001* | 3.81 | 1.92–7.56 | < 0.001* |
Lymph node invasion (Presence vs Absence) | 3.11 | 1.87–5.17 | < 0.001* | 2.54 | 1.47–4.37 | 0.001* |
Metastasis (Presence vs Absence) | 9.95 | 5.25–18.9 | < 0.001* | 4.04 | 1.70–9.61 | 0.002* |
MSI (MS unstable vs MS stable) | 0.53 | 0.22–1.23 | 0.138 | |||
EEF2K expression (Negative vs Positive) | 2.81 | 1.21–6.51 | 0.016* | 2.95 | 1.24–7.02 | 0.014* |