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Table 2 Log-rank test for characteristics of survival in 75 patients

From: Hypofractionated radiotherapy as a salvage treatment for recurrent hepatocellular carcinoma with inferior vena cava/right atrium tumor thrombus: a multi-center analysis

Variables n OS (mo) log-rank test
P values
Gender
 Female 9 12.2 ± 1.79 0.753
 Male 66 13.4 ± 1.15  
Age
  < 50 27 12.5 ± 1.43 0.613
  ≥ 50 48 13.6 ± 1.38  
Child-Pugh classification
 A 66 13.9 ± 1.09 < 0.001
 B 9 6.4 ± 0.80  
Performance status
 0 17 14.3 ± 2.39 0.728
 1 58 12.9 ± 1.11  
HBsAg
 Negative 6 15.5 ± 2.41 0.462
 Positive 69 12.9 ± 1.09  
AFP (μg/L)
  < 400 44 14.8 ± 1.59 0.041
  ≥ 400 31 10.9 ± 0.92  
No. of prior therapies
  < 4 35 12.8 ± 1.43 0.648
  ≥ 4 40 13.6 ± 1.44  
Intrahepatic tumor number
 Solitary 54 15.1 ± 1.25 < 0.001
 Multiple 21 7.6 ± 0.59  
LN metastases
 Absent 66 13.6 ± 1.11 0.223
 Present 9 10.6 ± 2.51  
Distant metastases
 Absent 55 14.7 ± 1.29 0.001
 Present 20 8.8 ± 0.58  
PTV
 TT 29 7.6 ± 0.61 < 0.001
 TT + PT 46 16.3 ± 1.34  
BED Dose (Gy)
  < 55 43 10.5 ± 0.97 0.001
  ≥ 55 32 16.6 ± 1.76  
Further radiotherapy
 Yes 37 17.3 ± 1.58 < 0.001
 No 38 8.6 ± 0.59  
Thrombus location
 IVC only 57 13.8 ± 1.13 0.205
 IVC + RA 18 11.6 ± 2.48  
  1. Abbreviations: OS overall survival, AFP α-fetoprotein, LN lymphonodus, TT tumor thrombus, PTV planning target volume, PT primary tumors, BED biological effective dose, IVC inferior vena cava, RA right atrium