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Table 1 Characteristics of included studies

From: Prognostic value of DNA aneuploidy in gastric cancer: a meta-analysis of 3449 cases

Publications No. of patients Age (year) Method Specimen Stage Follow-up
(month)
Treatment neclei Multiple sample form one case NOS
Ballantyne 1987 [10] 77 67 (43–88)a FCM PES NA 36 Surgery > 20,000 NA 7
Sasaki 1989 [11] 70 58.1 (33–80)b FCM FTS NA 48 Surgery 10,000 NA 7
Wyatt 1989 [12] 76 66 (40–88)a FCM PES NA 60 Surgery NA NA 8
Baretton 1991 [13] 125 66.8 ± 11.3b FCM PES NA 108 Surgery NA NA 8
Filipe 1991 [14] 116 64 (31–87)a FCM PES NA 108 Surgery > 10,000 NA 8
Kimura 1991 [15] 270 NA FCM PES I-IV 60 Surgery > 10,000 NA 8
Kakeji 1993 [16] 93 NA NA NA I-IV 60 Surgery 100 No 8
Suh 1993 [17] 103 55.9 (29–70)b FCM PES I-IV 24 Surgery > 10,000 NA 7
Flyger 1995 [18] 97 67 (23–85)a FCM PES NA 60 Surgery 10,000 NA 8
Tsuchiya 1995 [19] 127 NA FCM PES NA 96 Surgery+CT chemotherapy NA No 8
Victorzon 1996 [21] 242 NA NA NA I-IV 120 Surgery NA NA 8
Sakusabe 1996 [20] 216 56.7 (24–86)b FCM PES III 60 Surgery 10,000 No 8
Imada 1997 [22] 88 62.4b FCM FTS NA 36 Surgery+CT chemotherapy > 10,000 Yes 7
Omejc 1997 [23] 76 NA FCM PES I-IIIB 47 (14–67)a Surgery NA Yes 8
Abad 1998 [24] 76 70b FCM PES I-IV 43a NA 10,000 Yes 7
Hirose 1998 [25] 142 59b Cytofluorometry PES I-IV 132 Surgery NA NA 8
Danesi 2000 [26] 137 66.3b FCM PES I-III 80.8 (42.9–111.5)a Surgery 20,000 NA 8
Ikeguchi 2000 [27] 97 58 ± 13b FCM PES II 60 Surgery 10,000 NA 8
Russo 2001 [28] 69 NA FCM PES I-IV 95b Surgery NA Yes 8
Wu 2005 [29] 60 59.6a FCM NA NA 60 Surgery NA No 8
Nesi 2007 [30] 115 65.6 ± 11.3b FCM PES I-IV 84 Surgery > 20,000 Yes 8
Wiksten 2008 [31] 337 NA FCM PES NA 150 (52.8–249.6)a Surgery > 10,000 No 8
Belien 2009 [32] 221 71 (34–96)a FCM PES I-IV 21a Surgery NA No 7
Syrios 2012 [33] 212 61a ICM PES IV 65 Surgery+CT 200–300 NA 8
Nishimura 2017 [34] 207 A: 64.8 ± 10.9b
D: 62.1 ± 13.5b
LSC PES I-IV 60 RA NA NA 8
  1. A aneuploidy, D diploidy, PES paraffin embedded specimen, FTS fresh tissue specimen, FCM flow cytometry, ICM image cytometry, SCM static cytometry, LSC laser scanning cytometry, NA not available; a: median; b: mean; CT: chemotherapy