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Table 1 Frequency of GCT formation in 12 and 18-month-old Apc2 experimental genotypes on the background of Apcfl/fl. *One animal developed bilateral tumours

From: APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression

Age (months) Genotype Frequency of ovarian GCT
12 Apc2 +/+ 0/10 (0%)
12 Apc2 +/− 0/4 (0%)
12 Apc2 −/− 2*/10 (20%)
18 Apc2 +/+ 1/9 (11.1%)
18 Apc2 +/− 3/9 (33.3%)
18 Apc2 −/− 1/6 (16.67%)