Table 1 Frequency of GCT formation in 12 and 18-month-old Apc2 experimental genotypes on the background of Apcfl/fl. *One animal developed bilateral tumours
From: APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression
Age (months) | Genotype | Frequency of ovarian GCT |
|---|---|---|
12 | Apc2 +/+ | 0/10 (0%) |
12 | Apc2 +/− | 0/4 (0%) |
12 | Apc2 −/− | 2*/10 (20%) |
18 | Apc2 +/+ | 1/9 (11.1%) |
18 | Apc2 +/− | 3/9 (33.3%) |
18 | Apc2 −/− | 1/6 (16.67%) |