Skip to main content

Table 4 Adverse events

From: Selective TACE with irinotecan-loaded 40 μm microspheres and FOLFIRI for colorectal liver metastases: phase I dose escalation pharmacokinetic study

  Level 1 Level 2 Level 3  
All G3 All G3 All G3 All (%) G3 (%)
Hematologic toxicities
 Neutropenia 3 3 2 1 1 1 6 (66.7) 5 (55.6)
 Anemia 2 0 1 0 1 1 4(44.4) 1 (11.1)
 Thrombocytopenia 0 0 1 0 2 0 3 (33.3) 0 (0.0)
Non-hematologic toxicities
 Elevated AST 3 0 3 1 3 3 9 (100) 3(33.3)
 Elevated ALT 1 0 1 1 3 0 5(55.6) 1(11.1)
 Increased serum bilirubin 3 0 0 0 0 0 3 (33.3) 0 (0.0)
 Fever 0 0 2 0 0 0 2 (22.2) 0 (0.0)
 Abdominal Pain 2 0 2 0 3 0 7(77.8) 0 (0.0)
  1. G3 grade 3
  2. No grade 4 toxicities were found