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Table 3 Doses and injection times of TANDEM-IRI and FOLFIRI

From: Selective TACE with irinotecan-loaded 40 μm microspheres and FOLFIRI for colorectal liver metastases: phase I dose escalation pharmacokinetic study

  Level 1 Level 2 Level 3
Patient 1 2 3 4 5 6 7 8 9
Microsphere Dose (ml) 1.0 1.7 1.0 1.0 1.0 1.67 1.5 1.5 2.0
Irinotecan Dose (mg) 50 85 50 75 75 125 150 150 200
Injection Time (hr) 1.05 1.4 0.83 0.95 1.07 1.13 1.45 1.53 1.27
FOLFIRI Dose (mg) 228 246 262 265 214 232.5 234 226 255
Injection Time (hr) 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5
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