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Table 4 Identified protein candidates in the euploid vs. aneuploid comparison. IMS, imaging mass spectrometry; LC-MS/MS, liquid chromatograph-mass spectrometry

From: Spatial UBE2N protein expression indicates genomic instability in colorectal cancers

IMS [m/z, H+]

LC-MS/MS [m/z, H+]

Delta [Da]

Protein name

Accession UniProt

Regulation [euploid to aneuploid]

959.544

959.545

−0.001

Alpha-Enolase

ENOA_HUMAN

down

1118.661

1118.665

−0.004

down

959.544

959.513

0.031

Spectrin beta chain, non-erythrocytic 1

SPTB2_HUMAN

down

1203.898

1203.593

0.305

down

1203.898

1203.633

0.265

Transgelin-2

TAGL2_HUMAN

down

1384.045

1383.613

0.432

down

1043.533

1043.635

−0.102

Ubiquitin-conjugating enzyme E2 N

UBE2N_HUMAN

down

1203.898

1203.593

0.305

down

  1. The targets for subsequent immunohistochemical validation are presented in bold