Skip to main content

Advertisement

Table 4 Identified protein candidates in the euploid vs. aneuploid comparison. IMS, imaging mass spectrometry; LC-MS/MS, liquid chromatograph-mass spectrometry

From: Spatial UBE2N protein expression indicates genomic instability in colorectal cancers

IMS [m/z, H+] LC-MS/MS [m/z, H+] Delta [Da] Protein name Accession UniProt Regulation [euploid to aneuploid]
959.544 959.545 −0.001 Alpha-Enolase ENOA_HUMAN down
1118.661 1118.665 −0.004 down
959.544 959.513 0.031 Spectrin beta chain, non-erythrocytic 1 SPTB2_HUMAN down
1203.898 1203.593 0.305 down
1203.898 1203.633 0.265 Transgelin-2 TAGL2_HUMAN down
1384.045 1383.613 0.432 down
1043.533 1043.635 −0.102 Ubiquitin-conjugating enzyme E2 N UBE2N_HUMAN down
1203.898 1203.593 0.305 down
  1. The targets for subsequent immunohistochemical validation are presented in bold