Skip to main content

Table 5 Adjusted mean mammographic density measures according to anthropometric and lifestyle factors among postmenopausal women

From: Predictors of mammographic density among women with a strong family history of breast cancer

   Postmenopausal women (n = 59)
  Percent Density (%)   Dense Area (cm2)   Non-Dense Area (cm2)
n Mean1 PD 95% CI1 P 1 n Mean1 DA 95% CI1 P 1 n Mean1 NDA 95% CI1 P 1
Weight
 <77.0 kg 43 14.7 9.3-21.5   40 19.4 12.4-27.8   40 117.4 88.0-151.0  
 ≥77.0 kg 16 8.7 4.2-14.8 0.04 15 18.7 11.3-28.1 0.88 15 184.8 143.4-231.4 0.0007
Height
 <170 cm 47 13.4 8.8-19.1   43 20.3 13.8-28.2   43 137.3 111.7-165.6  
 ≥170 cm 12 15.4 8.2-24.7 0.56 12 18.3 9.4-30.0 0.63 12 98.3 66.9-135.7 0.01
TWA
 <43.0 MET-hrs/week 49 13.7 8.7-19.7   45 18.9 12.1-27.2   45 123.5 96.3-154.1  
 ≥43.0 MET-hrs/week 10 12.7 6.4-21.0 0.76 10 19.5 10.4-31.6 0.88 10 148.7 108.4-195.3 0.16
MVPA
 <27.0 METs/week 45 12.4 7.6-18.3   41 17.0 10.5-25.1   41 128.8 99.4-162.1  
 ≥27.0 METs/week 14 15.8 9.5-23.6 0.25 14 23.1 14.3-33.9 0.14 14 126.5 93.3-164.7 0.88
Smoking status
 Never 30 10.8 6.5-16.1 ref 29 16.4 10.3-23.9 ref 29 138.6 110.4-170.1 ref
 Former 22 19.5 13.2-27.0 0.003 20 26.9 18.1-37.4 0.01 20 108.4 81.1-139.8 0.04
 Current smoker 7 10.8 4.5-19.9 0.99 6 14 5.4-26.4 0.62 6 134.0 89.4-187.7 0.84
Age at first use
 <16 years 14 20.5 9.7-35.3   12 32.0 15.9-53.6   12 91.2 47.1-149.8  
 ≥16 years 15 26.2 14.8-40.8 0.35 14 36.9 21.9-55.8 0.58 14 111.3 68.8-163.9 0.42
Packs smoked
 <3 packs per week 8 18.8 7.9-34.3   7 35.0 17.0-59.4   7 126.2 70.7-197.7  
 ≥3 packs per week 21 25.1 14.7-38.3 0.26 19 35.2 21.3-52.7 0.98 19 100.8 63.2-147 0.28
Duration of use
 <14 years 13 24.3 12.1-40.8   11 37.5 20.1-60.3   11 121.7 71.0-186.1  
 ≥14 years 16 23.8 13.3-37.3 0.91 15 34.5 20.5-52.0 0.70 15 98.9 61.1-145.8 0.30
Alcohol use
 Never 5 16.8 7.6-29.6 ref 4 23.2 9.8-42.3 ref 4 102.6 59.0-158.3 ref
 Former 8 16.9 8.1-28.9 0.99 8 22.9 11.0-39.1 0.98 8 108.5 68.6-157.5 0.83
 Current user 46 14.1 9.4 19.8 0.58 43 20.4 13.7-28.4 0.70 43 128.7 103.1-157.1 0.30
Age at first use
 <18 years 20 12.1 6.9-18.8   17 17.7 10.2-27.2   17 138.9 106.0-176.2  
 ≥18 years 34 15.1 9.7-21.7 0.29 34 22.3 14.8-31.5 0.26 34 122.6 95.4-153.2 0.30
Drinks consumed
 <2 drinks per week 35 13.4 8.3-19.7   33 19.1 12.2-27.6   33 120.4 93.8-150.3  
 ≥2 drinks per week 19 14.9 8.8-22.5 0.62 18 23.4 14.6-34.3 0.32 18 143.5 110.2-181.2 0.14
  1. 1Adjusted least-square means, 95% confidence intervals, and P-values are from analyses using square root-transformed mammographic density measures. The adjusted least-square means and 95% confidence intervals were back-transformed
  2. All models were adjusted for age (continuous) and BMI (continuous) at the time of mammogram, parity (continuous), and mammogram modality (digital image, film scanned by study team, film scanned by imaging centre). The height and weight models were mutually adjusted for each other (continuous) instead of BMI. The physical activity models were additionally adjusted for smoking status (never, former, current). The smoking models were additionally adjusted for the number of alcoholic drinks consumed per week (continuous). The alcohol models were additionally adjusted for smoking status (never/ever). TWA, total weekly activity. MVPA, moderate-to-vigorous physical activity. METs, Metabolic Equivalent of Task