Skip to main content

Advertisement

Fig. 6 | BMC Cancer

Fig. 6

From: Expression patterns of small numbers of transcripts from functionally-related pathways predict survival in multiple cancers

Fig. 6

t-SNE profiling can further refine survival prediction in specific breast cancer subtypes. a Kaplan-Meier survival of patients with TNBC and Luminal A tumors. Patients and survival information were compiled from TCGA and ref. 23. b t-SNE clusters of only TNBC and Luminal A tumors from (a) using Wnt Pathway transcripts. These were derived from Additional file 1: Figure S2. c. Kaplan-Meier survival of each of the t-SNE groups from (b). NS = not significant (d). t-SNE profiling of TNBC and Luminal A tumors using Myc Pathway transcripts. (e). Kaplan-Meier survival of each of the t-SNE groups from (d). f Random Forest classification of transcripts from the Wnt Pathway that were the most deterministic of survival for all TNBC patients from (a). g Expression levels of Sfrp2 transcripts in each of the t-SNE clusters of TNBCs from (b). h. Random Forest classification of transcripts from the Myc Pathway that were the most deterministic of survival for all Luminal A patients from (a). i. Expression levels of Myc transcripts in each of the t-SNE clusters of Luminal A tumors from (d). j. Expression levels of Mxd2 transcripts in each of the t-SNE clusters of Luminal A tumors from (d)

Back to article page