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Table 3 Stch deficiency reduced plasma cells and Gm40600 expression induced by LPS

From: Gm40600 suppressed SP 2/0 isograft tumor by reducing Blimp1 and Xbp1 proteins

Gene Symbol

Total exon fragments

FPKM

Stchf/f

CD19creStchf/f

Stchf/f

CD19creStchf/f

Pax5

21,163

25,578

135.59

143.21

Bach2

2578

2608

8.17

7.22

Bcl6

660

590

6.38

4.99

Irf4

11,044

9245

81.82

59.86

Prdm1

2294

1288

17.02

8.35

Xbp1

6755

3460

176.95

79.21

Gm40600

391

14

25.96

0.81

  1. B220+ B cells from 7 to 9-week-old CD19creStchf/f mice and their WT littermates (Stchf/f) were stimulated for 3 days in vitro with 10 μg/ml LPS. On day 3 following LPS stimulation, the transcripts were determined by RNA-sequencing. Total exon fragments and FPKM (FPKM = total exon fragments / mapped reads (millions) / exon length (KB), Fragments per Kilo bases per Million reads) values of selected genes encoding Pax5, Bach2, Bcl6, Irf4, Prdm1, Xbp1, and Gm40600 are shown