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Fig. 5 | BMC Cancer

Fig. 5

From: A germline mutation in Rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome

Fig. 5

High levels of Rab43 protein expression were detected in the liver and colon cancer tissues, but not in their adjacent non-cancerous tissues (a-b) Representative Rab43 staining images in adjacent non-cancerous and colon cancer tissues obtained from the 54Y proband. a Rab43 staining score was displayed beside each image. The average levels of Rab43 protein from 15 adjacent non-cancerous colon tissue sections (slides) or 15 colon cancer tissue sections (slides) were summarized and compared in (b), ***p < 0.001 by Mann–Whitney test. c-d Representative Rab43 staining images in adjacent non-cancerous and liver cancer tissues from the proband’s father, the average levels of Rab43 protein from 15 adjacent non-cancerous liver tissue sections (slides) or 15 liver cancer tissue sections (slides) were summarized and compared in D, ***p < 0.001 by Mann–Whitney test

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BMC Cancer

ISSN: 1471-2407

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