Fig. 5
From: Peripheral ganglia in healthy rats as target structures for the evaluation of PSMA imaging agents
LNCaP PCa xenograft bearing mice. (a): [18F]DCFPyL, sagittal plane. (b): Maximal [18F]DCFPyL uptake (tumor voxel with highest intensity) plotted against tumor volume in five mice (R = 0.97, p = 0.0073). (c): Maximal [18F]DCFPyL uptake in the rat SCG compared to mouse tumor xenografts. Shown are mean ± standard deviation as well as individual data points. Variance was significantly higher in tumors compared to SCG (F (4, 5) = 78.4, p = 0.0002). (d): Signal-to-noise ratio measured with [18F]DCFPyL in rat SCG and mouse tumor xenografts. There was no significant difference between the two models. Abbreviations: B: bladder; K: kidney; SCG: superior cervical ganglion. Scale bar: 1 cm