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Table 4 Hazard Ratios for death. Brute and adjusted for age. Stage IV of the disease and mutated

From: Impact of genetic mutations and nutritional status on the survival of patients with colorectal cancer

Nutrition indicators HR brute (CI95%) p HR adjusted
(CI 95%) - Age
p HR adjusted
(CI 95%) - Stage IV of the disease
p HR adjusted
(CI 95%) – Mutated KRAS gene
p
BMI (kg/m2)
 Normal 1.0 1.0 1.0 1.0
 Undernourished 2.66 (0.88; 8.02) 0.081 2.32 (0.74; 7.23) 0.147 3.02 (0.97; 9.40) 0.056 1.83 (0.49; 6.89) 0.366
 Overweight / Obesity 0.31 (0.06; 1.53) 0.153 0.36 (0.07; 1.84) 0.225 0.38 (0.07; 1.93) 0.247 0.30 (0.05; 1.60) 0.160
Nutritional risk screening
 Without nutritional risk 1.0 1.0 1.0 1.0
 Nutritional rsk 8.77 (1.14; 67.1) 0.036 7.30 (0.88; 59.9) 0.064 8.16 (1.04; 63.7) 0.045 7.24 (0.91; 57.3) 0.060
PG-SGA
 Well nourished 1.0 1.0 1.0 1.0
 Moderetely / Severely malnourished 3.95 (1.11; 14.0) 0.033 3.10 (0.82; 11.7) 0.095 3.66 (1.02; 13.1) 0.046 4.28 (0.91; 20.1) 0.065
Phase angle
  > 5o 1.0 1.0 1.0 1.0
  < 5o 3.79 (1.10; 13.1) 0.035 2.85 (0.73; 11.1) 0.130 7.15 (1.71; 29.8) 0.007 3.07 (0.66; 14.1) 0.151
Visceral adipose tisse
  > 163.8 cm2 - male 1.0 1.0 1.0 1.0
  > 80.1 cm2 – female         
  < 163.8 cm2 – male 3.43 (1.03; 11.4) 0.044 4.08 (1.22; 13.6) 0.022 2.98 (0.88; 10.0) 0.077 4.94 (1.19; 20.5) 0.028
  < 80.1 cm2 – female         
Sarcopenia
 Without sarcopenic 1.0 1.0 1.0 1.0
 Sarcopenic 3.95 (1.06; 14.6) 0.040 4.08 (1.22; 13.6) 0.092 3.46 (0.92; 13.0) 0.066 3.12 (0.74; 13.1) 0.121
  1. HR Hazard ratio