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Table 2 Univariate analysis of risk factors for central lymph node metastasis

From: Risk factor analysis for predicting cervical lymph node metastasis in papillary thyroid carcinoma: a study of 966 patients

  OR 95%CI P value
  Lower Upper  
Gender (male vs. female) 1.59 1.16 2.18 0.004
Age (years)      < 0.001a
≤35 4.19 2.79 6.28 < 0.001
35–45 2.15 1.44 3.51 < 0.001
45–55 1.28 0.85 1.91 0.240
> 55 1    
Tumor size(cm)      < 0.001a
≤0.5 1    
0.5–1.0 1.86 1.20 2.89 0.006
1.0–2.0 4.24 2.71 6.62 < 0.001
> 2.0 6.78 4.11 11.18 < 0.001
Ultrasound feature
 Microcalcification (yes vs. no) 1.59 1.19 2.13 0.002
 Hypoechoic solid nodules (yes vs. no) 0.96 0.69 1.33 0.803
 Irregular shape (yes vs. no) 1.21 0.92 1.58 0.176
 Infiltrative margins (yes vs. no) 1.04 0.77 1.40 0.793
 Intra-nodular vascularity (yes vs. no) 1.64 1.24 2.18 0.001
Multifocality (yes vs. no) 1.45 1.10 1.92 0.009
Bilateral (yes vs. no) 1.50 1.09 2.06 0.012
Extrathyroidal extension (yes vs. no) 2.11 1.54 2.88 < 0.001
Distant metastasis (yes vs. no) 6.59 0.73 59.19 0.092
Hashimoto’s thyroiditis (yes vs. no) 1.19 0.91 1.56 0.195
TSH value   1.01 0.93 1.10 0.799
  1. a means the global p-values