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Fig. 3 | BMC Cancer

Fig. 3

From: Serum chitinase activity prognosticates metastasis of colorectal cancer

Fig. 3

Chitinase activity combined with N stage but not CEA level prognosticates metastasis in CRC patients. a Receiver Operating Characteristic (ROC) analysis showed that chitinase activity combined with N stage but not CEA played an effective role in metastasis prognosis for CRC patients with Stage І-III* Combination 1 denotes that chitinase activity and N stage. # Combination 2 denotes that chitinase activity and CEA level. Equation: Combination 1 = 0.066*chitinase activity+ 1.301*N stage (N0, 0; N1/N2, 1). Combination 2 = 0.2322*chitinase activity+ 0.06718*CEA (CEA < 5, 0; CEA ≥ 5, 1) Equation coefficients were obtained from multivariate Cox’s analysis. b Kaplan–Meier curves of metastasis probability of CRC patients subgrouped by chitinase activity and TNM. Hazard ratios and 95% CIs were calculated by the multi-variate Cox proportional hazards regression model, adjusted for age, sex, tumor location, histological type, tumor size, gross tumor type, schistosomiasis history and treatment methods as covariates

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