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Table 3 Multivariate Logistic Regression Analysis with BRCA mutation status as dependent variable in different clinical-pathological subsets of cases

From: BRCA germline mutation test for all woman with ovarian cancer?

Multivariate Logistic Regression

 

Odds ratio (95% CI)

p-value

Histology

 Non Epithelial vs Epithelial

0.48 (0.26÷0.83)

0.012

Stage

 II-III vs I

1.43 (0.76÷2.82)

0.28

CytoHistological Differentiation Grade

 III vs I-II

2.34 (1.34÷4.3)

0.003

Age

 > 50 years vs < 50 years

0.27 (0.18÷0.43)

< 0.0001

Ovarian Cancer history

 1st Degree Affected vs Not

3.91 (2.1÷7.04)

< 0.0001

Breast Cancer history

 1st Degree Affected vs Not

3.75 (2.46÷5.67)

< 0.0001