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Table 3 Multivariate Logistic Regression Analysis with BRCA mutation status as dependent variable in different clinical-pathological subsets of cases

From: BRCA germline mutation test for all woman with ovarian cancer?

Multivariate Logistic Regression
  Odds ratio (95% CI) p-value
Histology
 Non Epithelial vs Epithelial 0.48 (0.26÷0.83) 0.012
Stage
 II-III vs I 1.43 (0.76÷2.82) 0.28
CytoHistological Differentiation Grade
 III vs I-II 2.34 (1.34÷4.3) 0.003
Age
 > 50 years vs < 50 years 0.27 (0.18÷0.43) < 0.0001
Ovarian Cancer history
 1st Degree Affected vs Not 3.91 (2.1÷7.04) < 0.0001
Breast Cancer history
 1st Degree Affected vs Not 3.75 (2.46÷5.67) < 0.0001
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