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Table 2 Logistic Regression Analysis with BRCA mutation status as dependent variable in different clinical-pathological subsets of cases

From: BRCA germline mutation test for all woman with ovarian cancer?

Logistic Regression

 

Odds ratio (95% CI)

p-value

Histology

 Non Epithelial vs Epithelial

0.37 (0.25÷0.53)

< 0.0001

Stage

 II-III vs I

2.69 (1.7÷4.49)

< 0.0001

CytoHistological Differentiation Grade

 III vs I-II

2.7 (1.83÷4.1)

< 0.0001

Age

 > 50 years vs < 50 years

0.47 (0.34÷0.65)

< 0.0001

Ovarian Cancer history

 1st Degree Affected vs Not

4.9 (3.04÷7.73)

< 0.0001

Breast Cancer history

 1st Degree Affected vs Not

3.19 (2.22÷4.53)

< 0.0001