Table 1 Clinicopathological features of 338 patients who were treated with preoperative chemotherapy
Parameters (n = 338) | Number of patients (%) |
|---|---|
Age (years old) | 55 (24–78) |
Tumor size (mm) | 28.7 (9.2–119.8) |
Skin infiltration | |
 Negative / Positive | 288 (85.2%) / 50 (14.8%) |
Lymph node metastasis | |
 N0 / N1 / N2 / N3 | 114 (33.7%) / 128 (37.9%) / 63 (18.6%) / 33(9.8%) |
Estrogen receptor | |
 Negative / Positive | 187 (55.3%) / 151 (44.7%) |
Progesterone receptor | |
 Negative / Positive | 236 (69.8%) / 102 (30.2%) |
HER2 | |
 Negative / Positive | 214 (63.3%) / 124 (36.7%) |
Ki67 | |
 ≤ 15% / > 15% | 105 (31.1%) / 233 (68.9%) |
Intrinsic subtype | |
 Luminal BC / HER2BC / TNBC | 155 (45.8%) / 78 (23.1%) / 105 (31.1%) |
Objective response rate | |
 Non-Responders / Responders | 40 (11.8%) / 298 (88.2%) |
Pathological response | |
 Non-pCR / pCR | 222 (65.7%) / 116 (34.3%) |
TILs | |
 Low / High | 180 (53.3%) / 158 (46.7%) |
Hypertension | |
 No / Yes | 273 (80.8%) / 65 (19.2%) |
Number of medicine types for hypertension | |
 0 / 1 / 2 / 3 | 273 (80.8%) / 41 (12.1%) / 21 (6.2%) / 2 (0.6%) / 1 (0.3%) |
Calcium channel blockers | |
 No / Yes | 297 (87.9%) / 41 (12.1%) |
ACEi or ARBs | |
 No / Yes | 305 (90.2%) / 33 (9.8%) |
Beta-blockers | |
 No / Yes | 326 (96.4%) / 12 (3.6%) |
Diuretics | |
 No / Yes | 331 (97.9%) / 7 (2.1%) |