Table 4 Clinicopathological characteristics of HCC with NAFLD patients in the low ITIH4 and high ITIH4 groups
|  | Low ITIH4 group (n = 28) | High ITIH4 group (n = 27) | P value |
|---|---|---|---|
ITIH4 intensity | 8893.7 (±699.7) | 17,809.9 (±712.5) | < 0.0001 |
Gender (male) | 21 (75.0%) | 22 (81.5%) | 0.56 |
Age | 73 (56–86) | 72 (59–90) | 0.84 |
Obesity | 15 (53.6%) | 11 (40.7%) | 0.22 |
Diabetes | 16 (57.1%) | 15 (56.6%) | 0.91 |
Hypertension | 12 (42.9%) | 11 (40.7%) | 0.87 |
Child-Pugh score | 5.3 (±0.1) | 5.4 (±0.1) | 0.63 |
Fibrosis a (F3, 4) | 13 (46.4%) | 19 (35.9%) | 0.09 |
Stage b (III, IV) | 10 (35.7%) | 12 (44.4%) | 0.51 |
Tumor size (cm) | 4.3 (±0.7) | 6.3 (±0.7) | 0.03 |
Tumor number (≥2) | 11 (39.3%) | 8 (29.6%) | 0.45 |
Tumor differentiation (poorly) | 6 (21.4%) | 9 (33.3%) | 0.31 |
AFP (ng/ml) | 512.8 (±3232.2) | 8242.5 (±3354.3) | 0.10 |
PIVKA-II (mAU/ml) | 7613 (±12,000) | 25,841.6 (±12,453) | 0.30 |
Vascular invasion (+) | 4 (14.3%) | 4 (14.8%) | 0.96 |
Curability (R0 or 1) | 26 (92.9%) | 25 (92.6%) | 0.97 |