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Table 4 Number of macrometastases in sentinel node and risk of metastases in non-sentinel nodes

From: Determinants for non-sentinel node metastases in primary invasive breast cancer: a population-based cohort study of 602 consecutive patients with sentinel node metastases

SN removed Macro- metastases Total Negative Non-SN Positive Non-SN Positive Non-SN Stratified analysis Combined analysis
(n) (n)   (n) (n) (%) OR (95% CI) OR (95% CI)a OR (95% CI) OR (95% CI)a
1 0 47 39 8 17.0 1.00 1.00 1.00 1.00
1 69 44 25 36.2 2.77 (1. 12-6.85) 2.65 (1.05–6.66) 2.77 (1. 12-6.85) 2.65 (1.05–6.66)
Unknown 2 1 1
2 0 51 45 6 11.7 1.00 1.00 0.65 (0. 21-2.04) 0.65 (0. 21-2.07)
1 105 60 45 42.8 5.62 (2. 21-14.33) 4.83 (1.87–12.49) 3.66 (1.56–8.58) 3.09 (1.30–7.39)
2 52 20 32 61.5 12.00 (4.33–33.23) 11.12 (3.97–31.19) 7.80 (3.03–20.04) 7.43 (2.83–19.50)
3 0 59 51 8 13.5 1.00 1.00 0.76 (0. 26-2.22) 0.68 (0. 23-2.02)
1 58 39 19 32.7 3.11 (1. 23-7.83) 3.68 (1.32–10.24) 2.37 (0.93–6.07) 2.15 (0.82–5.64)
2 28 14 14 50.0 6.37 (2. 23-18.23) 6.30 (1.99–19.99) 4.87 (1.69–14.10) 4.18 (1.40–12.50)
3 21 6 15 71.4 15.94 (4.77–53.18) 16.96 (4.42–65.12) 12.19 (3.62–41.05) 10.02 (2.89–34.81)
4 0 24 21 3 12.5 1.00 1.00 0.70 (0. 17-2.91) 0.57 (0. 13-2.49)
1 29 22 7 24.1 2.23 (0.51–9.77) 3.34 (0.55–20.15) 1.55 (0.50–4.85) 1.56 (0.49–4.94)
2 11 7 4 36.3 4.00 (0.71–22.43) 9.46 (1. 26-70.85) 2.79 (0.66–11.82) 2.92 (0.67–12.65)
3 14 4 10 71.4 17.50 (3. 28-93.49) 17.18 (2.34–126.2) 12.19 (3.04–48.77) 9.25 (2. 22-38.53)
4 5 2 3 60.0
  1. Stratified analysis; comparisons within groups defined by number of removed SNs. Combined analysis; all groups compared using one SN with only micro-metastases as reference
  2. aStratified and combined analysis adjusted for screening, tumour type, and multifocality