Table 2 Potential determinants for non-sentinel node metastases
Determinants | Category | Negative Non-SN | Positive Non-SN | OR 95% CI | OR 95% CIa |
|---|---|---|---|---|---|
Screening | No | 197 | 112 | 1.00 | 1.00 |
Yes | 190 | 88 | 0.81 (0.58–1.15) | 0.81 (0.54–1.21) | |
Unknown | 4 | 11 | 4.84 (1.50–15.55) | 4.70 (1.36–16.19) | |
Age | ≤50 | 103 | 48 | 1.00 | 1.00 |
51–74 | 239 | 131 | 1.18 (0.79–1.76) | 1.50 (0.53–2.06) | |
≥75 | 49 | 32 | 1.40 (0.80–2.46) | 1.08 (0.45–2.60) | |
Menopause Status | Pre | 104 | 49 | 1.00 | 1.00 |
Post <5ys | 42 | 15 | 0.76 (0.38–1.50) | 0.79 (0.34–1.86) | |
Post ≥5ys | 231 | 139 | 1.28 (0.86–1.90) | 1.21 (0.60–2.44) | |
Unknown | 14 | 8 | 1.21 (0.48–3.08) | 1.45 (0.52–4.05) | |
Tumour size | T1 | 220 | 111 | 1.00 | 1.00 |
T2 | 120 | 73 | 1.21 (0.83–1.74) | 1.11 (0.74–1.66) | |
T3 & T4 | 6 | 4 | 1.32 (0.36–4.78) | 0.78 (0.19–3.14) | |
Unknown | 45 | 23 | 1.01 (0.58–1.76) | 0.76 (0.40–1.44) | |
Tumour type | Ductal | 331 | 159 | 1.00 | 1.00 |
D & L | 5 | 9 | 3.75 (1.24–11.36) | 2.93 (0.92–9.37) | |
Lobular | 41 | 38 | 1.93 (1. 19-3.12) | 1.73 (1.01–2.97) | |
Others | 14 | 5 | 0.74 (0. 26-2.10) | 0.85 (0. 29-2.50) | |
Histological grade | I | 82 | 36 | 1.00 | 1.00 |
II | 176 | 96 | 1.24 (0.78–1.98) | 0.88 (0.53–1.46) | |
III | 132 | 78 | 1.35 (0.83–2.18) | 0.94 (0.54–1.65) | |
Unknown | 1 | 1 | 2.28 (0. 14-37.43) | 1.23 (0.07–21.34) | |
Estrogen receptor | Positive | 358 | 187 | 1.00 | 1.00 |
Negative | 33 | 23 | 1.33 (0.76–2.34) | 1.04 (0.47–2.34) | |
Unknown | 0 | 1 | – | – | |
Progesterone receptor | Positive | 319 | 159 | 1.00 | 1.00 |
Negative | 72 | 50 | 1.40 (0.93–2.09) | 1.17 (0.66–2.07) | |
Unknown | 0 | 2 | – | – | |
Her-2 status | Negative | 248 | 135 | 1.00 | 1.00 |
Positive | 33 | 28 | 1.56 (0.90–2.69) | 1.52 (0.82–2.82) | |
Unknown | 110 | 48 | 0.80 (0.54–1.19) | 0.88 (0.55–1.39) | |
Multifocality | No | 247 | 108 | 1.00 | 1.00 |
Yes | 63 | 66 | 2.40 (1.59–3.62) | 2.20 (1.41–3.44) | |
Unknown | 81 | 37 | 1.04 (0.67–1.64) | 0.99 (0.61–1.60) | |
Vascular invasion | No | 166 | 75 | 1.00 | 1.00 |
Yes | 60 | 31 | 1.14 (0.68–1.91) | 1.13 (0.64–1.98) | |
Unknown | 165 | 105 | 1.41 (0.98–2.03) | 1.31 (0.86–1.99) |