Skip to main content

Table 2 Potential determinants for non-sentinel node metastases

From: Determinants for non-sentinel node metastases in primary invasive breast cancer: a population-based cohort study of 602 consecutive patients with sentinel node metastases

Determinants Category Negative
Non-SN
Positive
Non-SN
OR 95% CI OR 95% CIa
Screening No 197 112 1.00 1.00
Yes 190 88 0.81 (0.58–1.15) 0.81 (0.54–1.21)
Unknown 4 11 4.84 (1.50–15.55) 4.70 (1.36–16.19)
Age ≤50 103 48 1.00 1.00
51–74 239 131 1.18 (0.79–1.76) 1.50 (0.53–2.06)
≥75 49 32 1.40 (0.80–2.46) 1.08 (0.45–2.60)
Menopause Status Pre 104 49 1.00 1.00
Post <5ys 42 15 0.76 (0.38–1.50) 0.79 (0.34–1.86)
Post ≥5ys 231 139 1.28 (0.86–1.90) 1.21 (0.60–2.44)
Unknown 14 8 1.21 (0.48–3.08) 1.45 (0.52–4.05)
Tumour size T1 220 111 1.00 1.00
T2 120 73 1.21 (0.83–1.74) 1.11 (0.74–1.66)
T3 & T4 6 4 1.32 (0.36–4.78) 0.78 (0.19–3.14)
Unknown 45 23 1.01 (0.58–1.76) 0.76 (0.40–1.44)
Tumour type Ductal 331 159 1.00 1.00
D & L 5 9 3.75 (1.24–11.36) 2.93 (0.92–9.37)
Lobular 41 38 1.93 (1. 19-3.12) 1.73 (1.01–2.97)
Others 14 5 0.74 (0. 26-2.10) 0.85 (0. 29-2.50)
Histological grade I 82 36 1.00 1.00
II 176 96 1.24 (0.78–1.98) 0.88 (0.53–1.46)
III 132 78 1.35 (0.83–2.18) 0.94 (0.54–1.65)
Unknown 1 1 2.28 (0. 14-37.43) 1.23 (0.07–21.34)
Estrogen receptor Positive 358 187 1.00 1.00
Negative 33 23 1.33 (0.76–2.34) 1.04 (0.47–2.34)
Unknown 0 1
Progesterone receptor Positive 319 159 1.00 1.00
Negative 72 50 1.40 (0.93–2.09) 1.17 (0.66–2.07)
Unknown 0 2
Her-2 status Negative 248 135 1.00 1.00
Positive 33 28 1.56 (0.90–2.69) 1.52 (0.82–2.82)
Unknown 110 48 0.80 (0.54–1.19) 0.88 (0.55–1.39)
Multifocality No 247 108 1.00 1.00
Yes 63 66 2.40 (1.59–3.62) 2.20 (1.41–3.44)
Unknown 81 37 1.04 (0.67–1.64) 0.99 (0.61–1.60)
Vascular invasion No 166 75 1.00 1.00
Yes 60 31 1.14 (0.68–1.91) 1.13 (0.64–1.98)
Unknown 165 105 1.41 (0.98–2.03) 1.31 (0.86–1.99)
  1. aAdjusted for screening, age, menopause status, tumour size, tumour type, histological grade, estrogen status, progesterone status, HER2 status, multifocality, lymphovascular invasion