Determinants for non-sentinel node metastases in primary invasive breast cancer: a population-based cohort study of 602 consecutive patients with sentinel node metastases

Table 1 Potential determinants in relation to non-sentinel node status

Determinants	Category	Total	Negative Non-SN		Positive Non-SN
Determinants	Category	Total	N	%	N	%
Screening	No	309	197	50.4	112	53.1
	Yes	278	190	48.6	88	41.7
	Unknown	15	4	1.0	11	5.2
Age	≤50	151	103	26.3	48	22.7
	51–74	370	239	61.1	131	62.1
	≥75	81	49	12.5	32	15.2
Menopause Status	Pre	153	104	26.6	49	23.2
	Post < 5 ys	57	42	10.7	15	7.1
	Post ≥5 ys	370	231	59.1	139	65.9
	Unknown	22	14	3.6	8	3.8
Tumour size	T1	331	220	56.3	111	52.6
	T2	193	120	30.7	73	34.6
	T3 & T4	10	6	1.5	4	1.9
	Unknown	68	45	11.5	23	10.9
Tumour type	Ductal	490	331	84.7	159	75.4
	D & L	14	5	1.3	9	4.3
	Lobular	79	41	10.5	38	18.0
	Other	19	14	3.6	5	2.4
Histological grade	I	118	82	21.0	36	17.1
	II	272	176	45.0	96	45.5
	III	210	132	33.8	78	37.0
	Unknown	2	1	0.3	1	0.5
Estrogen receptor	Positive	545	358	91.6	187	88.6
	Negative	56	33	8.4	23	10.9
	Unknown	1	0	0.0	1	0.5
Progesterone receptor	Positive	478	319	81.6	159	75.4
	Negative	122	72	18.4	50	23.7
	Unknown	2	0	0.0	2	0.9
HER2 status	Negative	383	248	63.4	135	64.0
	Positive	61	33	8.4	28	13.3
	Unknown	158	110	28.1	48	22.7
Multifocality	No	355	247	63.2	108	51.2
	Yes	129	63	16.1	66	31.3
	Unknown	118	81	20.7	37	17.5
Vascular invasion	No	241	166	42.5	75	35.5
	Yes	91	60	15.3	31	14.7
	Unknown	270	165	42.2	105	49.8

ISSN: 1471-2407