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Fig. 1 | BMC Cancer

Fig. 1

From: Long non-coding RNA HOXB-AS3 promotes myeloid cell proliferation and its higher expression is an adverse prognostic marker in patients with acute myeloid leukemia and myelodysplastic syndrome

Fig. 1

Identification of HOXB-AS3 as a prognostic biomarker and overview of its locus in human HOXB. a The numbers of genes influenced overall survival in TCGA AML cohort and NTUH AML cohort. b The neighborhood of HOXB-AS3 locus in human HOXB cluster. The genomic data from ENCODE project was taken from UCSC genome browser. The exon localizations of eight HOXB-AS3 isoforms and HOXB5, HOXB6, and HOXB7 genes are shown. Arrows indicate the transcription direction of these genes. The NCBI Reference Sequence (RefSeq) numbers were labeled in the end of each variant. c PhyloCSF analysis for predicting the noncoding nature of HOXB-AS3. Exon 1, exon 4, exon 5 and exon 6 are zoom-in to see the details of PhyloCSF scores of the specific exons. All PhyloCSF scores are negative in the exons of HOXB-AS3

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BMC Cancer

ISSN: 1471-2407

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