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Table 1 Histologic and clinical characteristics of non-small cell lung cancer patients tested in this study

From: EGFR exon 20 insertion mutations and response to osimertinib in non-small-cell lung cancer

 

Adenocarcinoma

Squamous

Others a

Total

Total cases

1820

290

206

2316

 Median age

60(26–92)

62(30–88)

60(12–83)

61(12–92)

 Sex, M/F

917/903

247/43

144/62

1308/1008

EGFR mutant cases

1021

11

63

1095

 Frequency in total

56.1%

3.8%

30.6%

47.3%

 Median age

60(26–86)

64(38–89)

57(27–74)

60(26–89)

 Sex, M/F

397/624

5/6

28/35

430/665

EGFRex20ins cases

49

0

4

53

 Frequency in EGFR mutant

4.8%

0

6.3%

4.8%

 Frequency in total

2.7%

0

1.9%

2.3%

 Median age

57(31–85)

–

56.5(49–70)

57(31–85)

 Sex, M/F

26/23

–

2/2

28/25

  1. a Other pathological type in NSCLC, including adenosquamous lung cancer, NSCLC not otherwise specified, large cell lung cancer, neuroendocrine carcinoma and sarcomatoid carcinoma
  2. M/F male/female; EGFRex20ins, epidermal growth factor receptor exon 20 insertions, NSCLC non-small cell lung cancer