Fig. 4
From: Prognostic value of TOP2A in bladder urothelial carcinoma and potential molecular mechanisms
Cell proliferation, migration and invasion capacity was inhibited after TOP2A knockdown in bladder cancer cells. a TOP2A mRNA and protein expression levels in different bladder cancer cell lines. b The growth curves of J82 and 5637 cells between control and TOP2A knockdown groups. c The effect of TOP2A knockdown on tumor growth in nude mouse xenograft models. d Knockdown of TOP2A significantly decreased cell migration capacity in wound-healing assay. e Knockdown of TOP2A significantly reduced cells invading through Matrigel.NC = negative control. *, p < 0.05, **, p < 0.01. At least three independent replicates were performed for each experiment