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Fig. 4 | BMC Cancer

Fig. 4

From: MiR-890 inhibits proliferation and invasion and induces apoptosis in triple-negative breast cancer cells by targeting CD147

Fig. 4

Effects of miR-890 upregulation on the proliferation, apoptosis and invasion in TNBC cells. a The proliferation of MDA-MB-231 and HCC-70 cells 24–72 h after being infected with the indicated virus determined by CCK-8 assay. b Apoptosis in MDA-MB-231 infected with indicated lentivirus. Left panel: representative plots of MDA-MB-231 undergoing indicated treatments, the x-coordinate is the FITC channel and the y-coordinate shows PI staining, the lower left panel represents living cells, the lower right panel shows early apoptotic cells, the upper left panel shows necrotic cells and the upper right panel shows late apoptotic cells. Right panel: Quantification of apoptosis for the indicated treatments (including early and late apoptotic). c Invasion data of the HCC-70 cells 72 h after being infected with the indicated virus determined by a transwell assay.** P < 0.01, *P < 0.05. The tests were carried out on three biological triplicates, and data are expressed as the mean ± SD

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