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Table 1 Top transcripts in patients with metastatic lung cancer based on hierarchical clustering

From: Circulating tumor cell and cell-free RNA capture and expression analysis identify platelet-associated genes in metastatic lung cancer

Genes

Plasma detection

CTC detection

CCL5

A,B,C

B

CLU

A,B,C

B

GPX1

A,B,C

B

AKT3

A,B,C

 

ARHGDIB

A,B,C

 

SPARC

A,B,C

 

SRGN

A,B,C

 

TNXB

A,B,C

 

THBS1

B,C

B

BAI1

B,C

 

CLDN1

B,C

 

EGF

B,C

 

FHL1

B,C

 

PDK1

B,C

 

PLEKHO1

B,C

 

RBL1

B,C

 

RBX1

B,C

 

TGFB1

B,C

 

GIMAP4

B

B

ITGB3

C

C

PECAM1

C

B

LRG1

 

B,C

PKN1

 

B,C

  1. Only genes satisfying at least two cutoff criteria are shown. A, genes consistently showing higher expression based on plasma and CTC analyses; B and C, first and second tier of rare cancer-specific events. See Material and Methods for details. Bold face, genes forming a tight (confidence score > 0.9) cluster by interaction analysis using String database
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BMC Cancer

ISSN: 1471-2407

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