Table 1 Patients characteristics: number [No] and percentages [%] of patients
From: Adjuvant chemoradiation in pancreatic cancer: impact of radiotherapy dose on survival
Variable | Value | No of patients [%] | No of patients [%] treated with < 45 Gy | No of patients [%] treated with ≥ 45 and < 50 Gy | No of patients [%] treated with ≥ 50 and < 55 Gy | No of patients [%] treated with ≥ 55 Gy | p value |
|---|---|---|---|---|---|---|---|
Age | Median (range) | 63.0 (29–85) | 64.4 (38–81) | 64.0 (41–84) | 63.9 (29–86) | 62.0 (35–78) | .479 |
Tumor diameter (cm) | Mean (SD) | 2.82 ± 1.51 | 2.95 ± 1.48 | 3.12 ± 1.42 | 3.00 ± 1.31 | .190 | |
Gender | Male | 239 [46.5] | 11 [42.3] | 31 [43.1] | 156 [47.0] | 41 [48.8] | .410 |
Female | 275 [53.5] | 15 [57.7] | 41 [56.9] | 176 [53.0] | 43 [51.2] | ||
Ca 19.9 (units/mL) | < 90 | 114 [22.1] | 5 [19.2] | 21 [29.2] | 67 [20.2] | 21 [25.0]. | .076 |
≥ 90 | 137 [26.7] | 4 [15.4] | 16 [22.2] | 83 [25.0] | 34 [40.5] | ||
Unknown | 263 [51.2] | 17 [65.4] | 35 [48.6] | 182 [54.8] | 29 [34.5] | ||
Tumor site | Head | 432 [84.0] | 22 [84.6] | 66 [91.6] | 272 [81.9] | 72 [85.7] | .408 |
Body | 26 [5.1] | 2 [7.7] | 1 [1.4] | 17 [5.1] | 6 [7.1] | ||
Tail | 36 [7.0] | 2 [7.7] | 2 [2.8] | 27 [8.2] | 5 [6.0] | ||
Unknown | 20 [3.9] | 0 [0.0] | 3 [4.2] | 16 [4.8] | 1 [1.2] | ||
Type of resection | DCP | 315 [61.2] | 14 [53.8] | 41 [56.9] | 190 [57.2] | 70 [83.3] | <.001 |
DP | 61 [11.9] | 3 [11.6] | 4 [5.6] | 43 [13.0] | 11 [13.1] | ||
TP | 21 [4.1] | 4 [15.4] | 4 [5.6] | 12 [3.6] | 1 [1.2] | ||
PPP | 117 [22.8] | 5 [19.2] | 23 [31.9] | 87 [26.2] | 2 [2.4] | ||
Grading | 1 | 34 [6.6] | 1 [3.8] | 5 [7.0] | 12 [3.6] | 16 [19.0] | <.001 |
2 | 119 [23.2] | 5 [19.2] | 18 [25.0] | 65 [19.6] | 31 [36.9] | ||
3 | 250 [48.6] | 13 [50.0] | 38 [52.7] | 171 [51.5] | 28 [33.3] | ||
4 | 45 [8.8] | 1 [3.8] | 6 [8.3] | 35 [10.5] | 3 [3.6] | ||
Unknown | 66 [12.8] | 6 [23.2] | 5 [7.0] | 49 [14.8] | 6 [7.2] | ||
Margins status | R0 | 132 [25.7] | 8 [30.8] | 14 [19.4] | 70 [21.1] | 40 [47.6] | .032 |
R1 | 61 [11.9] | 3 [11.5] | 4 [5.6] | 22 [6.6] | 32 [38.1] | ||
Unknown | 321 [62.4] | 15 [57.7] | 54 [75.0] | 240 [72.3] | 12 [14.3] | ||
Tumor diameter | < 30 mm | 68 [13.2] | 5 [19.2] | 9 [12.5] | 17 [5.1] | 37 [44.0] | .206 |
≥ 30 mm | 61 [11.9] | 2 [7.7] | 4 [5.6] | 24 [7.2] | 31 [36.9] | ||
Unknown | 385 [74.9] | 19 [73.1] | 59 [81.9] | 291 [87.7] | 16 [19.1] | ||
pT-stage | 1 | 33 [6.4] | 1 [3.8] | 5 [6.9] | 26 [7.9] | 1 [1.2] | .006 |
2 | 107 [20.8] | 4 [15.4] | 15 [20.8] | 81 [24.4] | 7 [8.3] | ||
3 | 341 [66.3] | 21 [80.8] | 48 [66.7] | 206 [62.0] | 66 [78.6] | ||
4 | 33 [6.4] | 0 [0.0] | 4 [5.6] | 19 [5.7] | 10 [11.9] | ||
pN-stage | N0 | 205 [39.9] | 9 [34.6] | 28 [38.9] | 150 [45.2] | 18 [21.4] | .001 |
N+ | 309 [60.1] | 17 [65.4] | 44 [61.1] | 182 [54.8] | 66 [78.6] | ||
Adjuvant CT | No | 308 [59.9] | 19 [73.1] | 48 [66.7] | 227 [68.4] | 14 [16.7] | <.001 |
Yes | 141 [27.5] | 3 [11.5] | 18 [25.0] | 54 [16.2] | 66 [78.6] | ||
Unknown | 65 [12.6] | 4 [15.4] | 6 [8.3] | 51 [15.4] | 4 [4.7] |