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Table 2 Multivariable Cox proportional hazards regression analysis of factors associated with two-year mortality of Jordanian cancer patients at KHCC who smoke (n = 2384)

From: Smoking cessation care can translate to lower hazard of death in the short-run in cancer patients - a retrospective cohort study to demonstrate the value of smoking cessation services within the treatment phase of cancer

Variable

HR (95% CI)

Patient group (with regards to being seen at cessation clinic)

 Smokers who were seen [within a year of diagnosis] more than once at the clinic and whose records indicated abstinence at atleast two follow-up points (group A)

Reference group

 Smokers who were seen [within a year of diagnosis] more than once at the clinic and whose records indicated abstinence at only one follow-up point (group B)

1.3 (0.65–2.6)

 Smokers who were seen [within a year of diagnosis] more than once at the clinic and whose records indicated no abstinence at any follow-up point (group C)

2.7 (1.4–5.0)*

 Smokers who were never seen at the clinic or were seen after a year from diagnosis (group D)

2.8 (1.7–4.6)*

Female (versus male)

0.67 (0.53–0.84)*

Marital status

 Married

Reference group

 Single

0.88 (0.62–1.2)

 Other

1.1 (0.74–1.6)

Age at diagnosis

 18–30

Reference group

 31–40

1.5 (0.91–2.4)

 41–50

1.6 (0.98–2.6)

 51–60

1.8 (1.1–2.9)*

 61–70

2.1 (1.3–3.5)*

  > 70

2.1 (1.2–3.5)*

Year of diagnosis

 2012

Reference group

 2013

0.83 (0.66–1.0)

 2014

0.84 (0.66–1.1)

 2015

0.89 (0.70–1.1)

 2016

0.72 (0.52–0.99)*

Geographic area

 Central

Reference group

 North

1.1 (0.83–1.4)

 South

0.91 (0.65–1.3)

Cancer site (type)

 Solid, tobacco-related: head, neck, respiratory, esophageal (reference group)

Reference group

 Solid, tobacco-related, other: cervical, pancreatic, liver, stomach, urinary

0.75 (0.60–0.93)*

 Solid, not tobacco-related

0.92 (0.72–1.2)

 Hematological, tobacco-related

0.76 (0.47–1.2)

 Hematological, not tobacco-related

0.20 (0.14–0.27)*

Stage

 Local (reference group)

Reference group

 In-situ

0.37 (0.10–1.6)

 Regional*

3.7 (2.5–5.4)*

 Distant and unstaged

13.1 (9.0–19.1)*

Received chemotherapy (yes/no)

0.49 (0.39–0.61)*

Received surgery (yes/no)

0.39 (0.31–0.50)*

Received radiation (yes/no)

0.73 (0.60–0.87)*

Received immunotherapy (yes/no)

0.81 (0.29–1.3)

Received hormonal therapy (yes/no)

0.18 (0.11–0.28)*

Received bone marrow transplant (yes/no)

0.46 (0.27–0.77)

Having diabetes

1.2 (0.94–1.4)

Having cardio- or cerebrovascular disease

0.99 (0.81–1.2)

Having respiratory disease

1.2 (0.89–1.5)

  1. *p < 0.05