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Fig. 8 | BMC Cancer

Fig. 8

From: Deletion of sorting nexin 27 suppresses proliferation in highly aggressive breast cancer MDA-MB-231 cells in vitro and in vivo

Fig. 8

The working model of SNX27 knockdown in the cancer development. Knockdown of SNX27 inhibits the proliferation and decreases the expression of Vimentin and Claudin-5, and increases the expression of E-cadherin and β-catenin, which impact on the cell adhesion and migrate. SNX27 could be considered a potential molecular target for controlling cancer growth and development

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