Fig. 6

Breast cancer of SNX27-KD MDA-MB-231 cells grew less than that of WT MDA-MB-231 cells in a nude mouse model. a Representative tumors harvested from the mice (n = 5 per group) which challenged with SNX27-KD and WT MDA-MB-231 breast cancer cells were showed in vivo and in vitro. b Volume and weight of tumors (n = 9 per group) harvested from the mice injected with SNX27-KD MDA-MB-231 cells was significantly lower than that of wildtype cancer cells. Data are analyzed with Welch’s t-test, and expressed with mean ± SD. *p < 0.05 vs. WT control, **p < 0.01 vs. WT control