Table 3 Cox proportional hazards model and competing risk analyses

From: Intracranial aneurysms formation after radiotherapy for head and neck cancer: a 10-year nationwide follow-up study

Variables	Aneurysms formation
	Adjusted			Competing risk analysis
	HR	95%CI	P value	HR	95%CI	P value
Group
NPC-RT	1.99	1.23–3.21	< 0.01	2.57	1.55–4.24	< 0.001
Non-NPC-NRT	0.60	0.26–1.35	0.21	0.70	0.32–1.56	0.38
Non-NPC-RT	1.00	reference		1.00	reference
Gender
Male	0.77	0.44–1.34	0.35	0.71	0.39–1.28	0.26
Female	1.00	reference		1.00	reference
Age
< 45	1.00	reference		1.00	reference
45–65	1.20	0.69–2.06	0.52	1.07	0.64–1.80	0.79
> 65	0.97	0.43–2.19	0.94	0.68	0.32–1.46	0.32
Comorbidity
Arrhythmia	1.08	0.56–2.07	0.82	1.07	0.57–2.02	0.83
HTN	2.01	1.22–3.31	< 0.01	2.14	1.34–3.43	< 0.01
DM	1.04	0.61–1.78	0.87	0.99	0.59–1.66	0.97
COPD	1.07	0.62–1.85	0.80	1.12	0.63–2.00	0.69
Dyslipidemia	0.88	0.53–1.46	0.61	0.98	0.60–1.58	0.92
CKD	0.93	0.33–2.58	0.88	0.92	0.32–2.64	0.87
CAD	1.51	0.88–2.61	0.14	1.59	0.92–2.74	0.10
Heart failure	0.32	0.08–1.34	0.12	0.29	0.07–1.20	0.09
Liver cirrhosis	1.41	0.61–3.28	0.43	1.15	0.48–2.73	0.76
Chemotherapy
Yes	1.71	0.97–3.00	0.06	1.37	0.83–2.26	0.21
No	1.00	reference		1.00	reference

Abbreviations: NPC-RT nasopharyngeal cancer patients with radiotherapy, Non-NPC–RT other head and neck cancer patients with radiotherapy, Non-NPC-NRT other head and neck cancer patients without radiotherapy, HTN hypertension, DM diabetes mellitus, COPD chronic obstructive pulmonary disease, CKD chronic kidney disease, CAD coronary artery disease, HR hazard ratio, CI confidence interval

Back to article page