Table 3 Absolute and relative frequencies of the MPL and CALR mutations
MPL Mutation | CALR Mutation | |||||||
|---|---|---|---|---|---|---|---|---|
Author | Technique | PV % (n) | ET % (n) | PMF % (n) | Technique | PV % (n) | ET % (n) | PMF % (n) |
Xu [35] | AS-PCR | 0 (0) | 1.0 (1) | 0 (0) | ND | ND | ND | ND |
Chen [40] | AS-PCR | 0 (0) | 1,4 (1) | 5,6 (1) | ND | ND | ND | ND |
Toyama [41] | Sequencing | 0 (0) | 2,4 (2) | 0 (0) | ND | ND | ND | ND |
Wu [49] | Real-time PCR | 0 (0) | 5,0 (4) | 6,0 (3) | Sequencing | 0(0) | 25,0 (2)0) | 20,0 (16) |
Labastida [55] | ARMS | 0 (0) | 12,5 (1) | 0 (0) | Fragment analysis | 0 (0) | 50,0 (4) | 25,0 (1) |
Trifa [15] | SNP | 0 (0) | 1,4 (2) | 4,2 (2) | SNP | 0 (0) | 29,3 (41) | 25,0 (12) |
Gadomska [70] | ND | ND | 5,3 (1) | 0 (0) | ND | ND | 31,6 (6) | 100 (2) |
Li [72] | Sequencing | ND | 0,9 (9) | 1,1 (1) | Sequencing | ND | 12,6 (132) | 12,1 (11) |
Schnittger S [46] | PCR | ND | 7,1 (44) | 13,2 (17) | ND | ND | ND | ND |
Misawa [73] | AS-PCR | 0 (0) | 4,7 (10) | 1,1 (1) | Fragment analysis | 0 (0) | 26,9 (57) | 21,6 (19) |
Gángó [74] | Sequencing | ND | 1,6 (7) | 7,1 (16) | Fragment analysis | ND | 24,5 (104) | 21,6 (49) |
Lin [58] | Sequencing | 0 (0) | 1,2 (5) | 2,7 (5) | Sequencing | 0 (0) | 22,7 (97) | 17,6 (33) |
Delic [66] | Sequencing | 0 (0) | 5,0 (2) | 10 (3) | Sequencing | 0 (0) | 25,0 (10) | 10,0 (3) |
Orvain [67] | Real-time PCR | ND | 2,2 (2) | 17,1 (6) | Fragment analysis | ND | 12,9 (12) | 20.0 (7) |
Kander [19] | ND | ND | ND | ND | Fragment analysis | ND | 33,3 (10) | 37,5 (3) |
Gardner [65] | ND | ND | ND | ND | Fragment analysis | 0 (0) | 33,3 (1) | 66,7 (2) |
Smaili [69] | ND | ND | ND | ND | Sequencing | ND | 50,0 (11) | 36,4 (4) |