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Table 2 Absolute and relative frequencies of the JAK2V617F mutation

From: Systematization of analytical studies of polycythemia vera, essential thrombocythemia and primary myelofibrosis, and a meta-analysis of the frequency of JAK2, CALR and MPL mutations: 2000–2018

Author Diagnostic criteria Technique PV % (n) ET % (n) PMF % (n)
Zhang SJ [32] No data AS-PCR 69.6 (16) 45.0 (18) 37.5 (3)
Suzuki R [34] WHO 2001 Sequencing 46.7 (7) 47.6 (10) 80.0 (4)
Xu W [35] WHO 2001 AS-PCR 62.5 (20) 42.2 (43) 38.5 (5)
Lucia E [36] WHO 2001 AS-PCR 90.2 (74) 72.1 (31) 63.2 (12)
Tefferi A [38] WHO 2001 RT-PCR 89.9 (80) 45.6 (26) 55.0 (33)
Toyama K [41] WHO 2008 AS-PCR 88.0 (22) 68.3 (56) 75.0 (6)
Benmoussa A [42] No data AS-PCR 89.5 (17) 62.5 (5) 33.3 (4)
Zhang X [44] No data AS-PCR 84.3 (43) 69.7 (46) 52.9 (9)
Ho C [45] No data HRM 76.2 (16) 46.9 (15) 80.0 (4)
da Silva R [43] No data PCR-RFLP 88.5 (46) 48.1 (39) 72.7 (8)
Kim H [49] WHO 2008 AS-PCR 88.5 (23) 57.1 (24) 85.7 (6)
Patriarca A [48] WHO 2008 Real-time PCR 100 (26) 63.6 (35) 66.7 (6)
Wu Z [50] WHO 2008 HRM Sequencing 82.5 (66) 56.3 (45) 58.0 (29)
Payzin K [51] WHO 2008 Real-time PCR 95.1 (77) 68.2 (88) 77.3 (17)
Labastida N [56] Conventional ARMS 62.5 (5) 35.7 (5) 25.0 (1)
Mahjoub S [54] WHO 2008 AS-PCR 72.7 (16) 47.1 (8) 66.7 (2)
Jaradat S [55] WHO 2001 Sequencing 70.4 (19) 31.3 (5) 14.3 (2)
Gardner J [66] WHO 2008 Fragment Analysis PCR 100.0 (7) 66.7 (2) 33.3 (1)
Didone A [62] WHO 2008 PCR-RFLP 95.0 (19) 71.4 (20) 40.0 (8)
Yildiz I [72] WHO Sequencing 73.9 (17) 61.8 (42) 55.6 (5)
  1. WHO World Health Organization, AS-PCR Allele-specific polymerase chain reaction, RT-PCR Reverse transcription polymerase chain reaction, HRM High-Resolution Melt, PCR-RFLP polymerase chain reaction- Restriction Fragment Length Polymorphism, ARMS Amplification-refractory mutation system