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Table 3 CT perfusion measurements

From: A prospective clinical trial on sorafenib treatment of hepatocellular carcinoma before liver transplantation

CTp measurements

Index tumor at baseline (mean ± SD)

Liver at baseline (mean ± SD)

P value

Mean % change index tumor 1w

P value

Mean % change liver 1w

P value

BV (ml/100 g)

23.1 ± 8.0

21.3 ± 12.4

0.60

−10.0

0.16

−19.1

0.06

BF (ml/100 g/min)

184.7 ± 141.1

102.6 ± 46.4

< 0.05

−10.9

0.16

−14.9

0.05

MTT (seconds)

13.8 ± 6.9

20.4 ± 9.7

0.08

11.5

0.94

−7.5

0.53

HAF (in %)

46.1 ± 21.1

31.6 ± 22.8

0.11

−13.4

0.27

47.4

0.30

AF (ml/100 g/min)

84.2 ± 77.0

30.1 ± 21.1

< 0.01

−16.9

0.10

19.1

0.69

PSIndex (ml/100 g/min)

26.0 ± 22.2

37.0 ± 26.0

0.30

59.8

0.31

52.1

0.18

  1. CT perfusion measurements in the index tumor and in background liver before treatment start and after one week (n = 12)