Skip to main content

Advertisement

Table 3 Relationships between clinical features and ALT and AST status

From: Prognostic significance of serum aspartic transaminase in diffuse large B-cell lymphoma

Characteristics ALT+ ALT P value AST+ AST P value
No. of cases No. of cases
Age (years)
 ≤60 16 85 0.100 27 74 0.447
 > 60 6 72 17 61
Sex
 Male 16 88 0.138 24 80 0.582
 Female 6 69 20 55
Stage
 III-IV 12 87 0.939 34 65 0.001
 I-II 10 70 10 70
ECOG PS
  ≥ 2 6 22 0.121 12 16 0.014
  < 2 16 135 32 119
LDH
 Over ULN 13 59 0.054 36 36 < 0.0001
 Normal 9 98 8 99
ENI
  ≥ 2 5 38 0.250 16 27 0.027
  < 2 17 119 28 108
IPI
 3–5 7 45 0.760 21 31 0.002
 0–2 15 112 23 104
B symptoms
 Positive 11 51 0.106 24 38 0.001
 Negative 11 106 20 97
COO (Hans)
GCB 6 71 0.111 13 64 0.038
Non-GCB 16 86 31 71
  1. Abbreviations: ALT alanine aminotransferase, AST aspartate aminotransferase, COO cell of origin, ECOG PS performance status of Eastern Cooperative Oncology Group, ENI extra nodal involvement, GCB germinal-center B-cell type, LDH lactate dehydrogenase, IPI International Prognostic Index