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Table 3 Relationship between immunohistochemical results and clinicopathological data

From: Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer

 

Tumor histology

Grade

Stage

Recurrence

VEGF-A

 IRS

ns

ns

ns

0.005

VEGF-C

 IRS

0.033

0.006

ns

ns

 PP

0.019

0.003

ns

ns

VEGF-D

 IRS

ns

0.040

ns

ns

 PP

0.008

0.016

ns

ns

VEGFR1

 IRS

< 0.001

< 0.001

ns

0.010

 PP

< 0.001

< 0.001

ns

0.003

 SI

ns

0.008*

ns

ns

VEGFR2

 IRS

0.027

ns

ns

ns

 PP

0.002

0.008

ns

ns

 Stroma

ns

ns

ns

ns

VEGFR3

 IRS

ns

0.004

ns

ns

 PP

0.005

0.004

ns

ns

 SI

ns

0.026*

ns

ns

  1. p values determined by Kruskal-Wallis test, *Pearson’s chi-squared test
  2. IRS immunoreactive score, PP percentage of positively stained cells, Recurrence recurrence of cancer
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